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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLD3
All Species:
18.18
Human Site:
S458
Identified Species:
40
UniProt:
Q8IV08
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IV08
NP_001026866.1
490
54705
S458
N
G
R
G
G
L
R
S
Q
L
E
A
I
F
L
Chimpanzee
Pan troglodytes
XP_524268
446
49752
Q415
G
R
G
G
L
R
S
Q
L
E
A
I
F
L
R
Rhesus Macaque
Macaca mulatta
XP_001094274
490
54730
S458
N
G
R
G
S
L
R
S
Q
L
E
A
I
F
L
Dog
Lupus familis
XP_853110
490
54674
S458
N
G
R
G
G
L
R
S
Q
L
E
A
V
F
L
Cat
Felis silvestris
Mouse
Mus musculus
O35405
488
54371
S456
N
G
H
G
G
L
R
S
Q
L
E
A
V
F
L
Rat
Rattus norvegicus
Q5FVH2
488
54381
S456
N
G
H
G
G
L
R
S
Q
L
E
A
V
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421399
517
59127
R464
S
P
T
N
L
Q
R
R
Q
Q
P
V
Q
E
Q
Frog
Xenopus laevis
Q6PB03
493
56202
D459
T
Q
S
A
G
T
S
D
T
I
Q
M
Q
L
Q
Zebra Danio
Brachydanio rerio
XP_001340066
482
54690
T451
T
S
A
S
A
S
S
T
V
Q
E
Q
L
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610093
494
55569
E463
G
I
G
L
V
L
S
E
T
F
E
T
E
T
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O17405
516
58554
R456
K
E
K
I
P
F
T
R
V
N
H
A
K
Y
M
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
98.5
97.3
N.A.
93.2
93.8
N.A.
N.A.
40.8
53.5
50.6
N.A.
41.2
N.A.
36.8
N.A.
Protein Similarity:
100
91
98.9
98.9
N.A.
97.1
96.9
N.A.
N.A.
58.4
69.9
68.1
N.A.
56.8
N.A.
55.2
N.A.
P-Site Identity:
100
6.6
93.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
13.3
6.6
6.6
N.A.
13.3
N.A.
6.6
N.A.
P-Site Similarity:
100
6.6
93.3
100
N.A.
93.3
93.3
N.A.
N.A.
20
20
20
N.A.
13.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
10
0
0
0
0
0
10
55
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
10
0
0
0
0
0
10
0
10
64
0
10
10
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
10
0
0
10
46
0
% F
% Gly:
19
46
19
55
46
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
19
0
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
10
0
10
0
0
0
0
0
10
0
10
19
0
0
% I
% Lys:
10
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
10
19
55
0
0
10
46
0
0
10
19
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% M
% Asn:
46
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
0
10
0
0
10
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
10
0
0
0
10
0
10
55
19
10
10
19
10
19
% Q
% Arg:
0
10
28
0
0
10
55
19
0
0
0
0
0
0
10
% R
% Ser:
10
10
10
10
10
10
37
46
0
0
0
0
0
0
0
% S
% Thr:
19
0
10
0
0
10
10
10
19
0
0
10
0
10
10
% T
% Val:
0
0
0
0
10
0
0
0
19
0
0
10
28
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _